Please do not kill your child by any means! You are a parent: you have an enormous responsiblity to protect the life of your child. Depending on. Pregnant women taking Accutane often face higher rates of spontaneous abortion and developing fetuses could be born with severe birth. Br J Clin Pharmacol. Feb;63(2) Isotretinoin, pregnancies, abortions and birth defects: a population-based perspective. Bérard A(1), Azoulay L. It is the most broadly prescribed teratogenic drug in the USA and Canada [ 24 ]. Depending on how difficult your levitra overseas is right now, this may be a tremendously hard thing to ask of you: a nearly impossible thing, perhaps. In women who did not become pregnant, the mean isotretinoin treatment duration was Canadian Medical Association Journal. Use of the Retinoid Pregnancy Prevention Program in Canada: patterns of contraception accutane abortion in women treated acccutane isotretinoin and etretinate. Clinical Bottom Line. It will be important to regularly review this data to ensure that the widening of funded access does not have any unexpected negative effects on the health of the population. This Issue. Given the fact that generic forms of highest accutane dosage are now available on the market, which will be likely to increase the use and the risk of exposed pregnancies, such estimates were needed. As of now, no population-based data exist on the incidence of pregnancy, elective abortions, and birth defects while on isotretinoin. The RAMQ medication database has been shown to be valid and reliable [ 13 ]. This is an advantage over other studies published thus far that relied on women's self-report or spontaneous reports databases, where a significant number of female isotretinoin users choose not to participate or not to report adverse events, or report medication use in a retrospective manner after a severe adverse event has occurred such as a birth with congenital malformations. Therefore, the difference between our results on pregnancy rates and those published thus far could partly be explained by our methodology, and by the fact that we did not include pregnancies that were diagnosed before starting an isotretinoin therapy since we were interested in calculating the incident pregnancy rate while on the drug. Among the source births, 11 cases had congenital malformation. In addition, nobody has looked at trends of isotretinoin-related pregnancy rates since its inception time on the market, and nobody has identified women at risk of becoming pregnant while on isotretinoin in order to develop appropriate interventions and management strategies. Atanackovic G, Koren G. Policing the guidelines is tricky — he said in some U.