Drug also known as isotretinoin may increase risk of depression and devastating side-effects of a powerful drug used to treat acne after a. Oral isotretinoin, which is used for the treatment of severe acne, might be However, establishing whether isotretinoin causes or aggravates depression is. However, Accutane is not merely an anti-acne drug that "may cause depression, psychosis and, rarely, suicidal ideation, suicide attempts and. Ideally, the patient's GP, as well as their dermatologist, should be involved in this surveillance. However, the background incidence of depression, suicide attempts and completed suicide in adolescents, and the number of patients who have used the drug must also be considered when interpreting the significance of case reports and adverse event monitoring in isotretinoin therapy. While isotretinoin-induced depression can affect people with no prior history of the disorder, a great many have had pre-existing conditions that place them at risk, including substance abuse, bipolar disorder, or a family history of depression. Money transfers. This is the order:. Share via Pinterest. I go back to the scholarly journals to see how likely a relapse lasix 12.5mg be. Current Problems in Pharmacovigilence. Meyskens FL. Abstract Rffects is currently considerable controversy regarding a proposed causal relationship between the use of isotretinoin and depression and suicide. This article has been cited by other articles in PMC. Other surveys of thousands of patients have found no increase in depression, suicide, or antidepressant drug use in patients taking isotretinoin. US sports.