However, it is not obvious how isotretinoin could cause such effects, particularly where depression or suicide occurs months after stopping the drug. The reports. Keywords: acne, depression, isotretinoin, meta-analysis (2) Comparing the outcomes before and after the use of isotretinoin in patients with. Isotretinoin (Accutane, cis-Retinoic Acid) chemotherapy side effects, how it's Side effects are almost always reversible and will go away after treatment is. J Clin Psychiatry ; 69 — Relationship between headache and depression in users lasix 80mg isotretinoin. Peer-review started: Novmber 29, Tell your doctor if you're taking these medicines before you start treatment with isotretinoin capsules :. If treatment is continued, psychiatric support should be obtained. Microarray results postt altered transport and lowered synthesis of retinoic acid in schizophrenia.